Alterations in Lipid Fraction Levels in Subclinical Hypothyroidism in North Indian Population

A data of serum lipid profile such as total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, very low density lipoprotein cholesterol and triglyceride from 100 patients in the age range of 15-65 years of both sex having subclinical hypothyroidism were compared with euthyroid controls to observe that whether subclinical hypothyroidism is associated with abnormal lipid levels or not in a population-based sample from Northern Indians study. A significant increase in triglycerides and very low density lipoprotein cholesterol levels were observed in patients of subclinical hypothyroidism with respect to euthyroid controls while a nominal increase in serum cholesterol, low-density lipoprotein and high-density lipoprotein levels were recorded. However, there was no statistical difference found in any of the lipid fraction levels with change in the severity of subclinical hypothyroidism. All these observation suggested that subclinical hypothyroidism did not have a marked impact on any of the fraction of lipids.